PDGF-BBbelongstothefamilyofdisulfide-linkedhomodimericandheterodimericgrowthfactors.PDGFisexpressedindifferentcelltypesandstoredinplateletgranulesreleaseduponplateletactivation.PDGFisoformsarepotentmitogensforconnectivetissuecellsandcaninducechemotacticresponsesinfibroblasts,smoothmusclecells,neutrophilsandmononuclearcells.PDGFalsoappearstoplayanimportantroleinneuronsurvivalandregeneration.RecombinantHumanPDGF-BBisanon-glycosylated,disulfidelinkedhomodimer,containingtwo109aminoacidchains,withatotalmolecularweightof24.3kDa.

• AccessionNumber:P01127
• Synonyms:GDGF,ODGF
• Purity:≥95%purity.DeterminedbyHPLC,reducingandnon-reducingSDS-PAGE,andUVspectroscopy
• Bioactivity:ED50typicallylessthan15ng/mL.ED50determinedbydose-dependentproliferationofhuman3T3cells.
• Animalcomponent-freeandcarrier-free
• Custompackagingavailable

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